Interim estimates of influenza vaccine effectiveness in 2012/13 from Canada's sentinel surveillance network, January 2013.

نویسندگان

  • D M Skowronski
  • N Z Janjua
  • G De Serres
  • J A Dickinson
  • A-L Winter
  • S M Mahmud
  • S Sabaiduc
  • J B Gubbay
  • H Charest
  • M Petric
  • K Fonseca
  • P Van Caeseele
  • T L Kwindt
  • M Krajden
  • A Eshaghi
  • Y Li
چکیده

The 2012/13 influenza season in Canada has been characterised to date by early and moderately severe activity, dominated (90%) by the A(H3N2) subtype. Vaccine effectiveness (VE) was assessed in January 2013 by Canada's sentinel surveillance network using a test-negative case-control design. Interim adjusted-VE against medically attended laboratory-confirmed influenza A(H3N2) infection was 45% (95% CI: 13-66). Influenza A(H3N2) viruses in Canada are similar to the vaccine, based on haemagglutination inhibition; however, antigenic site mutations are described in the haemagglutinin gene.

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عنوان ژورنال:
  • Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

دوره 18 5  شماره 

صفحات  -

تاریخ انتشار 2013